Uttar Pradesh University of Medical Sciences, Saifai was established in the year 2016 by the Government of Uttar Pradesh after reconstituting the Uttar Pradesh Rural Institute of Medical Sciences and Research, Saifai, which was established in the year 2005. The University was established by an Act no.15 of 2016 of the state legislature of Uttar Pradesh as a State University vide notification no. 742(2)/LXXIX-V-1-16-1(ka)-7-2015 dated 17.05.2016 In accordance with the Uttar Pradesh Extraordinary Gazette, 17 May, 2016; the University (Uttar Pradesh University of Medical Sciences) shall be constituted of five faculties namely, Medicine, Dental, Paramedical Sciences, Nursing and Pharmacy.The University is listed in UGC as State University under section 2(f) of the UGC Act, 1956.